Depot Injections

This is a specially formulated, sterilised, liquid preparation of Naltrexone that can be injected into deep muscle. The Naltrexone is slowly released over approximately one month. The advantage is that no operation is needed and therefore no lump or scar is visible. The disadvantage is that it only lasts approximately one month so more commitment from the patient is required to have it repeated as necessary without relapsing in between.

Currently, it does not have a product licence (see implants above).
Tablets

These are usually swallowed daily and it is best that consumption is supervised. If not taken for a couple of days, relapse to opiate use is possible.

They do have a product licence.
Implants

These are specially formulated, sterilised preparations of Naltrexone that can be inserted under the skin during a 20-30 minute minor surgical procedure. We currently offer a 3 month-acting* Naltrexone implant.

(* It is impossible to say precisely how long an implant will last in any individual. We 'approximate’ the duration of action from our experience and the studies available. It is what most people (e.g. 80%) can expect to get, but some (e.g.10%) get more and some (e.g.10%) get less.)

Implants do not have product licences yet and are still regarded as experimental. However, their use is ‘legal’ and evidence so far indicates that they are generally safe and effective. The Stapleford Centre and other clinics worldwide have implanted thousands of people over more than 10 years.

(NB. Medicines often get used without a product licence which is eventually granted.)
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